What is the key characteristic of drugs administered via the endotracheal tube (ETT) during CPR?

The key characteristic of drugs administered via the endotracheal tube (ETT) during CPR is that they are lipid-soluble. This is because lipid-soluble drugs can more easily cross cell membranes and enter systemic circulation when administered via this route.

When drugs are given through the ETT, they need to be in a form that can be quickly absorbed into the bloodstream. Lipid-soluble drugs possess this quality, enabling a faster therapeutic effect, which is critical in emergency situations like cardiac arrest. It's important to note that not all medications can be effectively administered this way; therefore, understanding which drugs are appropriate for ETT administration is essential for correct dosing and efficacy during a resuscitation attempt.

The other options highlight misconceptions about ETT medication administration: the absorption of drugs given through this route may not be consistent, the dosing does not follow standard IV doses due to differences in bioavailability, and while certain medications are recommended for ETT use, it is not accurate to say that no drugs should ever be used via this route.