How long can effective CPR sustain life without advanced interventions?

Effective CPR can sustain life for several minutes because it maintains a level of circulation and oxygen delivery to vital organs, including the brain. However, the brain is particularly sensitive to a lack of oxygen, and irreversible damage can start occurring after approximately 4-6 minutes of cardiac arrest. During this time, while CPR is being performed, some blood flow is maintained to the heart and brain, which can prevent immediate cellular death.

The 4-6 minute timeframe emphasizes the critical nature of timely intervention and the brain's reliance on a continuous supply of oxygenated blood. This is why immediate and effective CPR is crucial in an emergency situation, as it can be life-saving until advanced medical interventions, such as defibrillation or advanced airway management, can be initiated.